Oral Cavity Cancer

Oral Cancer in India: Causes, Treatments, Advances & Outcomes

Oral cancer refers to malignant tumors that originate in the oral cavity, including the lips, tongue, gums, inner cheeks, floor of the mouth, and hard palate. The most common type is Oral Squamous Cell Carcinoma (OSCC), an aggressive disease that can spread rapidly if not detected early.

Oral Cancer in India: A Major Health Concern

India bears one of the highest burdens of oral cancer globally, accounting for over one-third of worldwide cases. Each year, more than 140,000 new oral cancer cases are diagnosed, with a significant proportion detected at advanced stages.

  • High prevalence of tobacco and betel nut use
  • Late-stage diagnosis in 60–80% of patients
  • Higher incidence among middle-aged men

Causes & Risk Factors

Oral cancer in India is predominantly lifestyle-related. The most common risk factors include:

  • Tobacco smoking and chewing (gutka, paan, zarda)
  • Areca nut (betel nut) consumption
  • Excessive alcohol intake
  • HPV infection (selected cases)
  • Poor oral hygiene and nutritional deficiencies

Early Symptoms & Warning Signs

Early recognition of symptoms can be life-saving. Warning signs include:

  • Non-healing mouth ulcers
  • Red or white patches inside the mouth
  • Lumps or thickened oral tissues
  • Difficulty chewing or swallowing
  • Unexplained bleeding or numbness

Treatment Options for Oral Cancer

1. Surgery

Surgery is the primary treatment for early-stage oral cancer. Advanced cases may require microvascular reconstructive surgery using free flaps to restore speech, swallowing, and facial appearance.

2. Radiation Therapy

Radiotherapy is often used after surgery or combined with chemotherapy in advanced cases to eliminate residual cancer cells.

3. Chemotherapy

Chemotherapy is used alongside radiation or before surgery to shrink large tumors.

4. Targeted Therapy & Immunotherapy

Newer treatments target specific cancer pathways or enhance the immune response, offering hope for advanced and recurrent cases.

Recent Advances in Oral Cancer Care

Modern advances include AI-assisted diagnostics, improved radiation techniques, and refined reconstructive procedures that significantly improve outcomes and quality of life.

Outcomes & Survival

Survival rates depend heavily on the stage at diagnosis. Early-stage oral cancers have significantly higher cure rates, while advanced cases require multidisciplinary treatment.

Prevention & Early Detection

Avoiding tobacco, limiting alcohol, maintaining oral hygiene, and undergoing regular screenings are the most effective strategies to prevent oral cancer and ensure early diagnosis.

© 2025 Dr. Bhargaw Ilapakurty | ENT Specialist & Head & Neck Onco Surgeon